Annual Report 2013 - page 10

The billion dollar chall
‘It takes a village’ … of support
“We all have a unique genome
and epigenome. In simple terms,
our epigenome directs our
genome…tells it what to do,”
explains Dr. Benjamin
Neel, Research Director
for the Princess
Margaret Cancer
Centre. “Unfortunately,
mutations or changes
in our genome that
give rise to cancer
cannot be reversed or
fixed. However, it has been shown
in the laboratory that some
changes in our epigenome that
lead to cancer can be reversed.”
For several years now, it has been
a high priority of Dr. Neel to build
a strong team to exploit our
understanding of the workings
of the epigenome to prevent and
treat cancer. He is very pleased
that thanks to donor support
his team now has three strong
leaders in this area.
Dr. Daniel De Carvalho
The American Society of Clinical
Oncology (ASCO) named his
work in cancer epigenetics as
one of the top 20 major advances
in cancer research in 2012 in its
Annual Report on Progress Against
Cancer
.
Dr. Housheng He
As a young investigator, he has
already led seminal work in the
field of epigenetics, including 22
Epigenetic therapies are now being used t
1,2,3,4,5,6,7,8,9 11,12,13,14,15,16,17,18,19,20,...36
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