The Princess Margaret “Transformers”

TECHNOLOGY ISSUE THE GTxOR We built the Guided Therapeutics Operating Room. Find out what makes it so special. Pg. 4 LORRAINE ROBBINS One woman’s incredible cancer journey, from searching for answers to finding the team who’s helping Lorraine battle sarcoma. Pg. 6 ON THE COVER Dr. Gang Zheng has developed a unique nanoparticle. Read about his remarkable nanotechnology. Pg. 14 LEUKEMIA: KNOWING ITS SIGNATURE ROBERT KYLE A new technology platform is transforming Dr. Jean Wang’s research in acute myeloid leukemia. Pg. 17 He survived a heart transplant only to be diagnosed with cancer one year later. Read about Robert’s remarkable journey. Pg. 30 LIQUID BIOPSY FROM HOURS TO MINUTES TRACKING THE ENEMY Dr. Suzanne Kamel-Reid is searching for answers in patients’ blood. The results are incredibly promising. Pg. 19 Find out how artificial intelligence is accelerating cancer care at The Princess Margaret. Pg. 11 A radioactive tracer is allowing Dr. Alejandro Berlin and his team to track a patient’s cancer and target it for radiation. Precision medicine at work. Pg. 29 TABLE OF CONTENTS 3. Lauren Craig: Our Inspiration Guided Therapeutics Operating Room - GTxOR 4. We Built: Guided Therapeutics Operating Room 6. Lorraine Robbins: Our Inspiration 9. Surgical Oncology Team Accelerating Care With Artificial Intelligence 10. Machine Learning: Predicting Best Therapies And Drug Combinations 11. Hours To Minutes: AI Generating Personalized Radiation Treatments 13. The ‘brAIn’ Project Nanoparticles 14. The Ultimate Transformer 15. Ultra-Minimally Invasive Surgery Technology Harnessing The Power Of A Cell 16. Single Cell Technology 17. Leukemia: Knowing Its Signature Precision Genomics Medicine 18. Cancer Molecular Profiling 19. Liquid Biopsy: The Answer Is In Your Blood 19. CRISPR: Genetic Engineering 21. A Cancer Blood Test? The Ultimate Fusion Of Technologies Techna Institute 22. Exploiting Technology To Enhance Patient Care Radiation Medicine Program - MRgRT 24. We Invented: Leksell Gamma Knife - ICON 25. Radiation Medicine: Leading The Way 26. We Built: Magnetic Resonance-Guided Radiation Therapy Suite 28. Combined Imaging For A Precise Diagnosis 29. Tracking The Enemy 30. Robert Kyle: Our Inspiration The Human Side Of Technology 31. Touch-Screen Symptom Manager 31. DART: Distress Assessment And Response Tool 32. Real-Time Access To Health Information The Princess Margaret 32. Message From Our Foundation Board Chair 32. Clinical Trials At Princess Margaret Cancer Centre